Dr. Jeremy London, a heart surgeon, has returned with more advice on how to live healthier and improve overall well-being. This time, he’s sharing an important reminder for people over 40—though, in truth, it’s something everyone should consider regardless of age.

In one of his recent TikTok videos filmed alongside his sons, one of them asks, “Dad, what things would you avoid after the age of 40?”

Dr. London answers, “The top two on the list apply at any age. The first one would be alcohol.”

He continues, “If you really want to set yourself up for long-term health, limit or eliminate alcohol. It’s toxic to every cell in the body. I realize this can be difficult because alcohol is everywhere. It’s a personal choice, but be mindful.”

Health experts echo this warning. The Cleveland Clinic notes that alcohol does far more harm than most people assume. In addition to adding “empty” calories and contributing to weight gain, long-term drinking increases the risk of heart disease, liver cirrhosis, certain cancers, and even brain damage.

Research supports this as well. A major study published in The Lancet concluded that the level of alcohol consumption associated with the lowest health risk is none, indicating that even moderate drinking carries measurable negative effects.

An occasional drink may not cause significant harm, but according to most experts, reducing alcohol in midlife—or avoiding it entirely—is the safest choice for long-term health.

Dr. London also urges people to avoid smoking and vaping. “Next is smoking and vaping. I don’t think anyone would disagree that it’s bad for you. It increases your risk of lung cancer, heart attack, and stroke. Don’t vape, don’t smoke.”

He goes on to highlight the importance of getting enough sleep. “Don’t trade sleep for other activities. This is something I personally struggle with. Recovery is important throughout our lives, but it becomes even more essential as we get older.”

Finally, he offers one more piece of advice: “Avoid toxic people. Focus on and nurture your relationships with the people you care about and love, because in the end, that’s what truly matters.”